Derma RPX Review: Is This the Anti-Wrinkle Cream for You?

If you click a link on this page and make a purchase, we may receive a small commission at no extra cost to you. Learn more.

If you’re unwilling to commit to invasive surgery or visit a cosmetic healthcare provider to fight the signs of aging, your best bet is to rely on one of the hundreds of anti-aging creams on the market.

Unfortunately, many of these skincare products promise amazing results while claiming that they’re the only solution to eliminate wrinkles, saggy skin, and other signs of aging.

In this Derma RPX review, we take a look at a product that doesn’t only promise fewer wrinkles but will also eliminate dark circles under your eyes and reduce the appearance of under-eye bags.

Does it work? Read our review to find out what we thought of Derma RPX.

What Is Derma RPX?

derma rpx

Derma RPX is a prescription-free anti-aging cream that claims to improve your skin’s texture and appearance in as little as five minutes.

It’s commonly advertised on TV, claiming to be the best anti-wrinkle cream on the market.

There’s very little information about the manufacturer of Derma RPX, and you can only buy the product on their website or via online resellers.

As with many as-seen-on-TV products, the manufacturers promise a 90-day satisfaction guarantee where they will offer you a full refund minus the shipping and handling costs.

The manufacturer recommends using the cream after cleansing and before putting on foundation. It acts as an excellent first layer that will smooth the skin to allow makeup to go on smoothly and without caking.

How Does Derma RPX Work?

The central claim that Derma RPX makes is that it tightens skin, resulting in fewer wrinkles and bags under the eyes and a reduction in dark circles.

It does this by providing the skin with essential nutrients that the skin lacks as it begins to age.

The main active ingredient in Derma RPX is hyaluronic acid, which is a well-known skincare compound found in many anti-aging creams.

The manufacturer claims that hyaluronic acid works synergistically with the other active compounds to produce results in as little as five minutes.

Since many of the factors that promote wrinkles and aging occur in the deep layers of the dermis, the cream has to penetrate deeply while still working within five minutes.

The manufacturers explain that the unique combination of ingredients is what sets their serum apart from all other products on the market.



Surprisingly, Derma RPX doesn’t offer a comprehensive list of ingredients, and we were unable to find any ingredient list on the Derma site or on the packaging itself.

The ingredient description says that it’s a proprietary blend of minerals without directly stating what these compounds are.

The Federal Trade Commission (FTC) requires that cosmetic labels adequately disclose the identity and contents of the package.

The difficulty in finding this information on Derma RPX may raise some warning flags about its contents.

While the manufacturer doesn’t directly give an ingredient breakdown on their website, we did a bit of digging.

We found out that the compounds (potentially) used in the serum are mica and silica, along with active ingredients citric acid, green tea extract, and hyaluronic acid.

Unfortunately, we couldn’t find the concentrations of these compounds, which would dramatically affect how well the serum works.

Lower concentrations may be completely ineffective, while higher concentrations could cause significant allergies and other unwanted side-effects.

Hyaluronic Acid

Hyaluronic acid is naturally produced by the body, predominantly in the joints and skin. The compound acts as a humectant that attracts water, which keeps your joints lubricated and your skin soft and supple.

Your body produces less hyaluronic acid as you age, which leads to dryer and less supple skin, as well as an increase in joint pain. The most common use of synthetic hyaluronic acid is in the treatment of arthritis.

Still, it’s gained prominence as a skincare product that can reduce the appearance of wrinkles and improve skin condition.

Woman checking face skin and looking at the mirror

Hyaluronic acid is also an essential compound in wound healing. It controls inflammation and helps connect new blood vessels to the damaged skin area.

Currently, the main use of hyaluronic acid in the cosmetics industry is as an injectable dermal filler, where it is injected under the skinto reduce fine lines.

Its effectiveness as a topical cream or serum is less-well understood, but this hasn’t stopped companies from using it in their skin cream products.

Green Tea Extract

Green tea extract may help improve blood flow to the skin, promoting healing and the formation of new, healthy skin under old, dry skin.

Green tea is also a potent antioxidant, which protects your skin from UV damage and other environmental pollutants.

This preventative function may not give the cream any five-minute firming powers, but it’s an excellent preventive against further signs of aging, especially if you’re a person that spends a lot of time in the sun.


Mica is traditionally used as a colorant and is what gives Derma RPX its distinctive color. It provides an opaque covering, which may explain the serum’s ability to reduce the appearance of dark circles.

There are some concerns about mica toxicity, which may be a concern for some customers. However, typically mica concentrations in anti-wrinkle products are very low and shouldn’t present a health concern.


Silica is a mineral that plays a role in collagen production. Collagen is one of the main compounds in the skin that contributes to firmness and elasticity.

As people start to age, their skin produces less collagen, making skin more prone to sagging. Since the epidermis is less elastic, it starts to create folds, which become wrinkles.

An increase in collagen can help restore some of your skin’s natural elasticity, dramatically reducing the signs of skin aging.

Citric Acid

Citric acid is a gentle acid that encourages new epidermis growth while removing the old layer of dead, dry skin.

It’s significantly milder than many facial peels but can still help reveal younger, firmer skin, especially in combination with minerals like silica that improves collagen production.

Benefits of Derma RPX

Brunette Woman Touching Face Looking In Mirror At Bathroom

The manufacturers claim that Derma RPX offers the following benefits:

  • Uses mica to balance your skin tone and diminish the appearance of dark circles under the eyes.
  • Contains hyaluronic acid that promotes water retention. It combats dry skin as well as the appearance of fine lines and mild wrinkles.
  • Firms and smooths skin texture, which reduces under-eye bags and minimizes puffiness.
  • It produces noticeable effects within five minutes.
  • It prevents makeup from caking by smoothing out your skin’s texture.
  • It uses only natural ingredients that are safe and won’t cause allergic reactions or adverse side effects.
  • Suitable for both men and women over the age of 20 who are starting to experience symptoms of aging

Potential Side Effects And Drawbacks Of Derma RPX

While the manufacturer doesn’t report any side effects associated with using their product, some people may still experience an allergic reaction to the serum.

Hyaluronic acid is already found in your body and shouldn’t produce an allergic reaction. However, some people may react badly to citric acid, mica, or even the non-active ingredients in the product.

We often recommend that you do an allergy test when trying out a new product for the first time.

Apply a small amount to your inner arm and wait a couple of days. If your skin doesn’t react negatively, then it’s likely to be safe for use on your face.

If you’re concerned about any of the ingredients in Derma RPX, consult your healthcare provider before using the product.

They’ll give you unbiased answers to your health questions as well as whether Derma RPX is safe for you.

young woman checking her pimples in the mirror

Even without going into health questions, several items may be drawbacks to a potential customer:

  • The 15 ml bottle is tiny, and you’ll probably end up using all of your monthly supply in two or three weeks.
  • Requires at least two months of continuous use to provide visible results
  • Very little product information and no product specifications: no ingredient or allergen list.
  • Made-for-TV products tend to have aggressive advertising campaigns and poor customer service.
  • Full-money back guarantee doesn’t take into account the shipping and handling costs.
  • Unclear instructions on how to use the serum, particularly in how many times per day you should use it.

How To Use Derma RPX

Derma RPX is very easy to incorporate into your existing skincare routine. The recommended routine is:

  • Gently wash your face as usual. Rinse thoroughly to remove any residue and ensure you’ve removed all the moisture present on your face.
  • If possible, give your face several minutes to dry completely.
  • Apply a small, tear-drop sized amount of Derma RPX to your finger or the included contour tip.
  • Tap the product into the target area on your face, such as a wrinkle or under your eyes.
  • Wait five minutes before applying any makeup, if desired.

Frequently Asked Questions

Who Should Use Derma RPX?

The product is suitable for all people over the age of 20 who struggle with dark circles under their eyes, under-eye bags, or saggy skin around the eyes.

The official site shows both men and women using the product. All the ingredients work for both genders, meaning that it’s as effective for men as women.

Man wipes his face with a towel

How Often Should I Use Derma RPX?

Most customers use the product once to twice a day as part of their cleaning routine.

There’s no official information about how much or how often you should use the product, though using it too often may mean that you end up using all of your monthly supply too soon if you sign up for the subscription.

When Will I See Results?

Derma RPX claims that you’ll see results within five to ten minutes of application. These effects can last up to 10 hours, and consistent use produces more reliable outcomes.

Where Do I Buy Derma RPX?

You can buy Derma RPX via the official website or through several resellers.

If you purchase through the website and provide your name, email, and address, you’ll get signed up for a subscription service that you can opt out of at any time.

Once you’ve signed up, you’ll get two 15 ml/0.5 oz bottles that should last around two months.

Afterward, the billing cycle repeats every four weeks, and the company will ship two bottles every eight weeks. You can cancel of this subscription at any time. Shipping is free for subscribers, which is a nice bonus.

Is There A Money-Back Guarantee?

Yes. The company offers a 90-day money-back guarantee if you’re not satisfied with the product. However, while you’ll get your money back for the bottle, you still need to pay shipping and handling charges.

Can I Try It Before I Buy?

derma rpx

If you don’t want to commit to a full-size bottle, you can order a free tester from the website if you provide your name, email, and address.

While the tester itself is free, you’ll still have to pay for shipping and handling.

This smaller-sized bottle should be enough to determine if you’re allergic to the product, as well as discover if it works for you at all.

However, it’s important to note that opting into this trial will automatically sign you up for the subscription service.

You’ll have to manually cancel this subscription if you don’t want to pay for it after the initial tester.

What Do Other Customers Say?

We found very few reviews on the official website and instead had to rely on third-party sites to get a relatively unbiased opinion to see what customers thought of this product.

There are hundreds of customers that have tried Derma RPX, and the customer reviews are surprisingly mixed.

While some people love the effects of the product, some customers report that they didn’t see any results at all.

Some reviewers complained that the cream left a stiff residue that shone through their makeup, while others found it chalky and glue-like.

Many people struggled with the question of how much to use and how often to use it.

However, despite some negative reviews, others found the product to be effective against reducing the appearance of aging.

One reviewer said Derma RPX significantly reduced the bags under her eyes, while another said that the cream helped even out her skin tone without the need for makeup.

However, the positive reviews and stars were vastly outweighed by the negatives, which resulted in the cream getting a surprisingly low average rating.

Since results are very mixed, we recommend not relying on any particular review. Try the product for yourself, and if you have any other concerns, talk to your healthcare provider.


Final Verdict: Is Derma RPX Worth It?

The official Derma RPX site makes the bold claim that it is a five-minute solution to puffy eyes and other skin problems.

The product claims to use a proprietary blend of minerals to tighten and firm up skin and balanced skin tone.

Unfortunately, while these claims sound great, there’s very little evidence to support them, and we found several warning signs that the product probably doesn’t work as well as it should.

The fact that the Derma brand only has one product they sell on TV is already slightly suspicious.

The product also doesn’t have an ingredient list, and you can’t find any information on the brand itself, which is also a strong warning sign that this may be a waste of money.

Many customer reviews say that the cream doesn’t have any effect at all, while others say it made their face feel tight without addressing their underlying concerns and issues.

If you rely on reviews, you may be slightly worried about the low number of stars that this product gets. For every positive review, we found several that outright said the product didn’t work at all.

One reviewer even experienced a severe allergic reaction that left her skin worse off than before.

While fake reviews are a constant problem when online shopping, this product’s low ranking raises a few questions that don’t have satisfactory answers.

If you’re unconvinced by the low stars and poor reviews, you can still order a free tester from the site and try the product out for yourself, but don’t forget to cancel your automatic subscription directly afterward.

With such underwhelming results, we would strongly recommend choosing products with a proven track record, like LifeCell All-in-One Anti-Aging Treatment, which uses a collagen-based solution to reduce the appearance of wrinkles, puffy eyes, and dark circles.

Editors Choice
Derma RPX Review: Is This the Anti-Wrinkle Cream for You? 2


Our #1 Recommendation

  • Over One Million Sold
  • Clinically Proven and Effective
  • Best Selling Treatment 10 Years +
  • Cruelty-Free (Not Tested On Animals)

Derma RPX Review: Is This the Anti-Wrinkle Cream for You? 3

Avatar for Megan Foley

Megan has been a freelance writer and editor since 2016. In that time, she’s penned a diverse collection of articles for online publication, with a focus on skincare and beauty. From in-depth product reviews to concise marketing content, Megan is passionate about developing content that informs, entertains, and inspires.